
If a death really fit I might go for it, but in general, no, it's not something I'm open for. I haven't been in an RP scenario anywhere in all my years of RPing where a PC death had a positive impact on the story. It's always ended horribly, though often not right away--or at best just neutral. I realize there are other people out there who have had good experiences with it, but I, personally, have not, and with enough frequency that I'm just not a fan of it. I'm not going to subject other players to that without a good reason.
Injury, even catastrophic or career-ending? Definitely down for that. I tend to avoid it because it makes me feel like I'm taking away attention from other characters, but some of the most compelling RP I've done has been related to this. In other circles I have a reputation for being particularly brutal to my characters, but here I'm actively avoiding it because it can be construed as attention-seeking behavior. Once the character is somewhat well-established, sure. People have to have a reason to care before it becomes compelling subject matter for anyone but me. As I'm fond of saying, you have to build them up before you tear them down (and then build them back up again).
Injury, even catastrophic or career-ending? Definitely down for that. I tend to avoid it because it makes me feel like I'm taking away attention from other characters, but some of the most compelling RP I've done has been related to this. In other circles I have a reputation for being particularly brutal to my characters, but here I'm actively avoiding it because it can be construed as attention-seeking behavior. Once the character is somewhat well-established, sure. People have to have a reason to care before it becomes compelling subject matter for anyone but me. As I'm fond of saying, you have to build them up before you tear them down (and then build them back up again).