As far as quests go, I don't think there's really any stressed "dangers" of opening your gates, though those in the storyline that have opened them tend to be a little power-hungry about it.
If you wanted to come up with something, the stress of being unable to handle the aether might work, since we have examples of that happening in other places, I believe.
The closest thing that we have to a danger is the following:
If you wanted to come up with something, the stress of being unable to handle the aether might work, since we have examples of that happening in other places, I believe.
The closest thing that we have to a danger is the following: